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Advantage II made by Bayer is a monthly topical flea treatment for Dogs and Cats seven weeks and older that kills fleas within 12 hours of application. Its two main ingredients are: Imidacloprid, which affects the flea’s nervous system, and an insect growth regulator (IGR) known as Pyriproxyfen that stops juvenile fleas from reproducing by preventing their development into adulthood. Together, the two ingredients work to terminate the life cycle of fleas. Advantage flea treatment is waterproof and never expires if stored according to package specifications.

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